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Sulforaphane - An Amazing New Old Supplement -Roger Mason
Sulforaphane has been known about for decades. It is contained in broccoli sprouts and other cruciferous vegetables in small microgram amounts. Raw broccoli is three times more effective than cooked. Until recently there was almost no clinical proof of its benefits. It was also expensive to produce. Now we have both clinical proof and inexpensive sulforaphane. The new studies actually include humans as well as animals. The animal studies are overwhelming and important, but we will only quote some of the many human studies. The problem is that most all the companies who sell it only offer small 400 microgram (or less!) capsules. Source Naturals® does sell a broccoli sprout extract with 60 tablets of 1,000 mcg sulforaphane for about $12 from mega-corporations or on ebay (the official retail is $18.98). The label says, “2,000 mcg”, but the dose is 2 tablets. It would be a good idea to take one a day (1,000 half in mcg), or two a day (2,000 mcg) if you are treating a condition. Take half in the AM and the PM for best absorption. We simply cannot match their price on this, so we are not adding it to our supplements. If you go to www.greenmedinfo.com you can read the abstracts of 252 such studies. The fact it has so many proven benefits in human published studies shows it is an overall immunity enhancer, anti-oxidant, and anti-inflammatory- like beta glucan and vitamin D.
In the International Journal of Food Science (v. 63, 2012) real people lowered their insulin levels and improved their insulin resistance in only 4 weeks, with no change in diet or lifestyle. Diabetics were simply given broccoli extract. This was a classic double blind study. Blood sugar, insulin, and HOMA (insulin resistance) were all measured. This works much better than toxic, ineffective, expensive diabetes drugs such as Metformin, Farxiga, Januvia, etc. Read the article Insulin is Making You Fat. Insulin also stimulates aromatase activity, which raises estradiol and estrone. High blood sugar, insulin resistance, high insulin, metabolic syndrome, and diabetes are epidemic in Western countries. Sulforaphane is a powerful tool in curing blood sugar and insulin conditions. This should be standard medical treatment for all blood sugar/insulin conditions.
Inflammation is an overall health curse for our health. This is the defensive complex biological response of body tissues to harmful stimuli such as pathogens and irritants. In Food Chemistry v 173, 2015 inflammation in humans was dramatically reduced. “The consumption of broccoli sprouts modulated the excretion of biomarkers linked to inflammation.” Very sophisticated diagnostic tests were given to these patients to assess their inflammatory response. Reducing inflammation helps us to live longer and live better.
Gastritis, ulcers and Helicobacter pylori infections are epidemic in Western countries. Two thirds of the world population have toxic H. pylori bacteria in their stomachs. In Cancer Prevention Research v 2, 2009 people ate broccoli sprouts daily for two months. They got dramatic results with their digestion with no change in diet or lifestyle. Doctors can do nothing here except give people toxic drugs, which only make them worse. Read the article Good Health Begins with Good Digestion.
In Experimental Biology and Medicine v 232, 2007 sulforaphane was found to inhibit cancer growth in people. This was done at the famous Linus Pauling Institute. This works by inhibiting histone deacetylase (HDAC) activity, which promotes malignant growth. PC-3 prostate cancer cells were inhibited a full 40% just by giving the patients broccoli extract. This is nothing less than miraculous. Why isn’t sulforaphane standard medical treatment for ALL cancers? In the Journal of Nutrition v 139, 2009 the same inhibition of HDAC was achieved for inhibiting cancer and malignancy growth. Sulfoaphane is now officially classed as an HDAC inhibitor. “The ability of sulforaphane to target aberrant acetylation patterns, in addition to effect on phase 2 enzyme, make it an effective chemopreventive agent,” the doctors stated.
Liver cancer is common in parts of China due to airborne pollutants. In Carcinogenesis v 33, 2012 patients were given a broccoli sprout beverage daily. In only 7 days their urine proved they were excreting large amounts of carcinogenic toxins such as ethylene oxide and benzene. Liver disease of all types is now epidemic over the world. In another study men with fatty liver disease were give sulforaphane for 60 days. Their AST, ALT, y-GPT and 8-OHdG were all measured. With no change in diet they found this to be, "highly efective in improving liver function through reduction of oxidative stress". Their four parameters were greatly improved. This was in World Journal of Gastroenterology v 21, 2015.
Prostate disease is an epidemic in all developed countries. BPH is actually pandemic. Prostate cancer is now the second leading cause of cancer death in men. Males were given sulforaphane after having radical prostatectomy (surgical removal)for six months. This was in Cancer Prevention Research v 8, 2015. It took almost twice a long to double PSA levels in the treated group. In Investigation of New Drugs v 33, 2015 men with recurrent prostate cancer were give sulforaphane supplements. PSA levels fell and doubling time for PSA was reduced greatly. This just helps to verify the other studies. Sulforaphane should be used to both help prevent and cure all prostate disease.
Lung problems, especially asthma, are epidemic in the world today. Lung disease is a leading case of death. Asthmatics (Respiratory Research v 16, 2015) were given sulforaphane for only 14 days. There were give very exotic tests before and after such as "FEV1 response" and high resolution CT scans. The results were dramatic here and broncodilation and other parameters improved greatly. Imagine taking this for a year. Why aren’t doctors using this?
Everyone today breathes diesel exhaust particles, especially in Europe. These are very toxic and build up over time. A human study was published in Food Function v 5, 2014. People exposed to diesel exhaust were given sulforaphane in fruit juice for a mere 4 days. In only 4 days their nasal white blood count increased 85%. This is nothing less than incredible. In Clinical Immunology v 130, 2009 subjects were given sulforaphane to improve cure their upper airway inflammation. The doctors said, "Oral sulforaphane safely and effectively induces mucosal Phase II enzyme expression in the upper airway of human subjects." These kind of results are simply incredible.
Autism was almost unheard of until recently. The CDC claims 1 in 68 children in the U.S. are born with this now. Boys are four times more subject to autism. Doctors can do nothing here except drug them up with toxic poisons such as anti-psychotic drugs. This only makes them worse, not better. Children with autism were given sulforaphane (Proceedings of the NAC 111, 2014) for only four weeks. No change in diet or lifestyle was made. This was a very sophisticated double blind study with intricate psychological testing. The results were amazing...they, "had improvement in social interaction, abnormal behavior, and verbal communication." Why aren't doctors and parents taking advantage of this?
It gets better...adult schizophrenics were given sulforaphane (Clinical Psychopharmacology Neuroscience v 13, 2015. Oxidative stress is central here. The patients were given sulforaphane for only 8 weeks. They were then tested with the very sophisticated Positive/Negative Syndrome Scale and CogState Battery tests. Their cognitive function clearly improved with no other therapies. This should be standard practice with mental patients, along with a program of diet, lifestyle, hormone balance and other proven supplements. Drugging them with dangerous anti-psychotic drugs insures they will never improve, and only get worse.
Now we have a long list of published human studies showing amazingly diverse benefits from simply taking an inexpensive safe broccoli extract. This is due to the ability to reduce inflammation, reduce oxidation, and enhance immunity. All adults should take this. People under 40 with any kind of medical condition or illness should also take it. A mere $12 a month for something this powerful and effective.
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